Resveratrol-loaded solid lipid nanoparticles versus nanostructured lipid carriers: evaluation of antioxidant potential for dermal applications

GÖKÇE E. H. , KORKMAZ E., Dellera E., SANDRİ G., Bonferoni M. C. , Ozer O.

INTERNATIONAL JOURNAL OF NANOMEDICINE, cilt.7, ss.1841-1850, 2012 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 7
  • Basım Tarihi: 2012
  • Doi Numarası: 10.2147/ijn.s29710
  • Dergi Adı: INTERNATIONAL JOURNAL OF NANOMEDICINE
  • Sayfa Sayısı: ss.1841-1850

Özet

Background: Excessive generation of radical oxygen species (ROS) is a contributor to skin pathologies. Resveratrol (RSV) is a potent antioxidant. Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) can ensure close contact and increase the amount of drug absorbed into the skin. In this study, RSV was loaded into SLN and NLC for dermal applications.