Resveratrol-loaded solid lipid nanoparticles versus nanostructured lipid carriers: evaluation of antioxidant potential for dermal applications

GÖKÇE E. H. , KORKMAZ E., Dellera E., SANDRİ G., Bonferoni M. C. , Ozer O.

INTERNATIONAL JOURNAL OF NANOMEDICINE, vol.7, pp.1841-1850, 2012 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 7
  • Publication Date: 2012
  • Doi Number: 10.2147/ijn.s29710
  • Title of Journal : INTERNATIONAL JOURNAL OF NANOMEDICINE
  • Page Numbers: pp.1841-1850

Abstract

Background: Excessive generation of radical oxygen species (ROS) is a contributor to skin pathologies. Resveratrol (RSV) is a potent antioxidant. Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) can ensure close contact and increase the amount of drug absorbed into the skin. In this study, RSV was loaded into SLN and NLC for dermal applications.