Is ursodeoxycholic acid crucial for ischemia/reperfusion-induced ovarian injury in rat ovary?


AKDEMİR A. , Sahin C. , Erbas O., YENİEL A. Ö. , ŞENDAĞ F.

ARCHIVES OF GYNECOLOGY AND OBSTETRICS, vol.292, no.2, pp.445-450, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 292 Issue: 2
  • Publication Date: 2015
  • Doi Number: 10.1007/s00404-015-3646-9
  • Title of Journal : ARCHIVES OF GYNECOLOGY AND OBSTETRICS
  • Page Numbers: pp.445-450

Abstract

Ursodeoxycholic acid is frequently used in cholestatic liver diseases. Also, it protects hepatocytes against oxidative stress induced by hydrophobic bile acids. We investigated the anti-oxidative effect of ursodeoxycholic acid on ischemia/reperfusion injury after ovarian de-torsion in rats.