Deep tissue near-infrared imaging for vascular network analysis


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ŞEKER K., ENGİN M.

JOURNAL OF INNOVATIVE OPTICAL HEALTH SCIENCES, cilt.10, 2017 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 10 Konu: 3
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1142/s1793545816500516
  • Dergi Adı: JOURNAL OF INNOVATIVE OPTICAL HEALTH SCIENCES

Özet

Subcutaneous vein network plays important roles to maintain microcirculation that is related to some diagnostic aspects. Despite developments of optical imaging technologies, still the difficulties about deep skin vascular imaging have been continued. On the other hand, since hemoglobin concentration of human blood has key role in the veins imaging by optical manner, the used wavelength in vascular imaging, must be chosen considering absorption of hemoglobin. In this research, we constructed a near infrared (NIR) light source because of lower absorption of hemoglobin in this optical region. To obtain vascular image, reflectance geometry was used. Next, from recorded images, vascular network analysis, such as calculation of width of vascular of interest and complexity of selected region were implemented. By comparing with other modalities, we observed that proposed imaging system has great advantages including nonionized radiation, moderate penetration depth of 0.5-3mm and diameter of 1mm, cost-effective and algorithmic simplicity for analysis.