The aim of this study is to determine energy consumption of input and output used in raisin production and making a cost analysis in Aegean Region. Energy output-input analysis is generally done to determine the scope of environment and energy efficiency of agricultural production. In this study the cost of raisin production was calculated by Manisa Viticulture Research Institute's records in 2015. Costs of inputs and prices of raisin were obtained from various sources such as Turkish Statistical Institute, Aegean Exporters' Association and Turkish Ministry of Food, Agriculture and Livestock. The total energy input necessity for raisin production was 39,066.91 MJ/ha. The research results indicated that the total energy input used for raisin was mainly dependent on non-renewable energy forms (%97). The high ratio of non-renewable energy in the total used energy inputs causes negative effects on the sustainability in agricultural production. Among input energy sources, diesel oil, chemical fertilizers and electricity contained highest energy shares with 34.30%, 26.96%, and 22.50% respectively. The energy ratio and energy productivity were found to be 6.04 and 0.51 kg/MJ. Gross production value and total variable costs for raisin were $ 8,600 and $ 4,528.25, respectively. As a result of cost analysis, gross margin was calculated as $ 4,071.75.