Predictive role of laboratory markers and clinical features for recurrent Henoch-Schonlein Purpura in childhood: A study from Turkey


GÖKÇE Ş. , Kurugol Z. , KOTUROĞLU G. , ASLAN A.

MODERN RHEUMATOLOGY, cilt.30, ss.1047-1052, 2020 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 30 Konu: 6
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1080/14397595.2019.1690966
  • Dergi Adı: MODERN RHEUMATOLOGY
  • Sayfa Sayıları: ss.1047-1052

Özet

Objectives: Henoch Schonlein Purpura is the most common systemic vasculitis of the childhood. The objective of this study was to evaluate whether there is a clinical significance of laboratory parameters and clinical features on the prediction of the recurrent Henoch Schonlein Purpura in children. Methods: For recurrent Henoch Schonlein Purpura, several laboratory results and clinical features were examined to identify the predictor factors via the logistic regression model in 99 children with Henoch Schonlein Purpura. A p-value of Results: The demographic features and laboratory results were not found statistically significant between the two groups (p > .05). The multiple logistic regression model showed that the risk of recurrent Henoch Schonlein Purpura increased 17.2-fold in children with Henoch Schonlein Purpura affected by the four systems including skin, joint, kidney and gastrointestinal system [Odds Ratio (OR) 17.2, 95% CI 1.4-12; p < .001]. Conclusion: In our inpatient population, the laboratory characteristics were detected not to be a factor for the prediction of recurrence. However, the four systems including skin, joint, kidney and gastrointestinal involvement may be used as a predictive factor for recurrent HSP.