The natural colored cotton provides environmentally-friendly and cheap products. Because the elimination of dyeing process it is possible to save up dyeing and some finishing costs, Angora rabbit fiber is a specialty animal fiber with good softness, brightness, fineness and warmness. To produce healthy, ecological and wanner products these two fibers should be blended. In this study, to produce ring-spun yams, natural colored cotton and Angora rabbit fibers were blended with different blend ratios. Then, double face fabrics were knitted. On the front side of the fabric natural colored cotton/angora blended yams and on the back (next to skin) side pure natural colored cotton yams are used in order to prevent skin from uncomfortable feeling. For comparison, a control sample is knitted using 100% natural colored cotton yams in both sides. Thermal comfort properties of fabrics are measured. The effects of Angora fiber ratios in the blend and using different sides of fabrics next to skin are investigated. The results indicate that using Angora blended yams on the back side of the fabric gives warmer feeling and thermal insulation values increase however water vapor permeability decreases with the increment of Angora rabbit fiber ratio.