Rhabdomyolysis is a condition of muscle tissue release including after necrosis of muscle due to a direct or indirect muscle injury. Rhabdomyolysis is mostly asymptomatic but hypovolemic shock, cardiac arrhythmias or acute renal failure may be seen afterwards. Herein, we presented two rare cases of rhabdomyolysis; a patient who developed acute kidney injury associated with rhabdomyolysis following an epileptic seizure and a patient who developed acute kidney injury associated with rhabdomyolysis following swimming. With these rare cases, we wanted to emphasize that epileptic seizures and excessive exercise such as swimming may cause rhabdomyolysis just like the well-known causes. Early treatment of rhabdomyolysis is very important and should be suspected if findings of rhabdomyolysis are seen after these events.