Exenatide preserves trabecular bone microarchitecture in experimental ovariectomized rat model


EMINOV E., HORTU İ. , AKMAN L. , Erbas O., YAVAŞOĞLU A. , ÇIRPAN T.

ARCHIVES OF GYNECOLOGY AND OBSTETRICS, vol.297, no.6, pp.1587-1593, 2018 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 297 Issue: 6
  • Publication Date: 2018
  • Doi Number: 10.1007/s00404-018-4776-7
  • Title of Journal : ARCHIVES OF GYNECOLOGY AND OBSTETRICS
  • Page Numbers: pp.1587-1593
  • Keywords: Osteoporosis, Postmenopause, Glucagon-like peptide, Exenatide, GLUCAGON-LIKE PEPTIDE-1, VERTEBRAL FRACTURES, RECEPTOR, MEN, HISTOMORPHOMETRY, OSTEOPOROSIS, RELEASE, WOMEN, GENE, MASS

Abstract

Purpose The aim of this study is to investigate effects of exenatide (Glucagon-Like Peptide Agonist) replacement on bone mineral density (BMD) and microarchitecture in a surgical menopause-induced osteoporosis model in rats.