Exenatide preserves trabecular bone microarchitecture in experimental ovariectomized rat model

EMINOV, Elmin; HORTU, İSMET; AKMAN, LEVENT; Erbas, Oytun; YAVAŞOĞLU, ALTUĞ; ÇIRPAN, TEKSİN

doi:10.1007/s00404-018-4776-7

Exenatide preserves trabecular bone microarchitecture in experimental ovariectomized rat model

EMINOV E., HORTU İ. , AKMAN L. , Erbas O., YAVAŞOĞLU A. , ÇIRPAN T.

ARCHIVES OF GYNECOLOGY AND OBSTETRICS, vol.297, no.6, pp.1587-1593, 2018 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 297 Issue: 6
Publication Date: 2018
Doi Number: 10.1007/s00404-018-4776-7
Title of Journal : ARCHIVES OF GYNECOLOGY AND OBSTETRICS
Page Numbers: pp.1587-1593
Keywords: Osteoporosis, Postmenopause, Glucagon-like peptide, Exenatide, GLUCAGON-LIKE PEPTIDE-1, VERTEBRAL FRACTURES, RECEPTOR, MEN, HISTOMORPHOMETRY, OSTEOPOROSIS, RELEASE, WOMEN, GENE, MASS

Abstract

Purpose The aim of this study is to investigate effects of exenatide (Glucagon-Like Peptide Agonist) replacement on bone mineral density (BMD) and microarchitecture in a surgical menopause-induced osteoporosis model in rats.