Preparation of Ca-alginate biopolymer beads and investigation of their decorporation characteristics for Sr-85, U-238 and Th-234 by in vitro experiments

Gok C., Gerstmann U., Hoellriegl V., AYTAŞ Ş.

RADIATION PROTECTION DOSIMETRY, vol.153, no.1, pp.47-55, 2013 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 153 Issue: 1
  • Publication Date: 2013
  • Doi Number: 10.1093/rpd/ncs088
  • Page Numbers: pp.47-55


The aim of this work was to investigate whether Ca-alginate biopolymer beads (CaABBs) can be used to reduce the bioavailability of radionuclides in the gastrointestinal tract of humans. The uptake of strontium, uranium and thorium from a simulated gastrointestinal system was studied by in vitro techniques using CaABBs. This agent was prepared from Na-alginate through cross-linking with divalent calcium ions according to the egg-box model. The effects of process variables such as pH of the gastrointestinal juice, incubation time and solid-to-solution ratio for the removal of radionuclides from the gastrointestinal juice were investigated. The results suggest that CaABBs are a potent material for reducing the bioavailability of radionuclides with a high uptake efficiency in the gastrointestinal tract.