Toxoplasma gondii destroys Her2/Neu-expressing mammary cancer cells in vitro using a continuous feed medium approach


Atalay Şahar E., Döşkaya M. , Karakavuk M., Can H., Gül A., Gürüz A. Y. , ...More

JOURNAL OF INFECTION IN DEVELOPING COUNTRIES, vol.14, no.10, pp.1204-1209, 2020 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 14 Issue: 10
  • Publication Date: 2020
  • Doi Number: 10.3855/jidc.12820
  • Title of Journal : JOURNAL OF INFECTION IN DEVELOPING COUNTRIES
  • Page Numbers: pp.1204-1209

Abstract

Introduction: Toxoplasma gondii is an opportunistic protozoan and can be grown using several human cell lines. Breast cancer is the second leading cause of cancer death in women. Her2/Neu-expressing mammary cancer cell lines called TUBO can be grown in vitro. In recent years, protozoan parasites have become popular means of use in cancer therapy research. In this study, we analyzed whether T. gondii tachyzoites can destroy TUBO cells using a novel continuous feed medium approach.