Methylprednisolone induces apoptosis by interacting with the JAK/STAT pathway in HL-60 and K-562 leukemic cells

Kaymaz, BURÇİN; SELVİ, Nur; SAYDAM, GÜRAY; ŞAHİN, FAHRİ; KOSOVA, BUKET

doi:10.1179/102453312x13221316477859

Methylprednisolone induces apoptosis by interacting with the JAK/STAT pathway in HL-60 and K-562 leukemic cells

Atıf İçin Kopyala

Kaymaz B. , SELVİ N., SAYDAM G. , ŞAHİN F. , KOSOVA B.

HEMATOLOGY, cilt.17, ss.93-99, 2012 (SCI İndekslerine Giren Dergi)

Cilt numarası: 17 Konu: 2
Basım Tarihi: 2012
Doi Numarası: 10.1179/102453312x13221316477859
Dergi Adı: HEMATOLOGY
Sayfa Sayıları: ss.93-99

Özet

Objective: To determine the gene expression profiles of the JAK/STAT pathway members STAT3, STAT5A, STAT5B at both mRNA and protein levels in HL-60 and K-562 leukemia cells that were undergoing apoptosis following high-dose methylprednisolone (MP) treatment.