Multicenter experience in hematopoietic stem cell transplantation for serious complications of common variable immunodeficiency


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WEHR C., GENNERY A. R. , Lindemans C., Schulz A., Hoenig M., MARKS R., ...More

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, vol.135, no.4, pp.988-0, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 135 Issue: 4
  • Publication Date: 2015
  • Doi Number: 10.1016/j.jaci.2014.11.029
  • Title of Journal : JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
  • Page Numbers: pp.988-0

Abstract

Background: Common variable immunodeficiency (CVID) is usually well controlled with immunoglobulin substitution and immunomodulatory drugs. A subgroup of patients has a complicated disease course with high mortality. For these patients, investigation of more invasive, potentially curative treatments, such as allogeneic hematopoietic stem cell transplantation (HSCT), is warranted.