A contemporary review of molecular candidates for the development and treatment of childhood medulloblastoma

SUMER-TURANLIGIL N. C. , Cetin E. Ö. , UYANIKGİL Y.

CHILDS NERVOUS SYSTEM, cilt.29, ss.381-388, 2013 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 29 Konu: 3
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1007/s00381-012-2014-3
  • Dergi Adı: CHILDS NERVOUS SYSTEM
  • Sayfa Sayısı: ss.381-388

Özet

Medulloblastoma is the most common pediatric central nervous system tumor; however, the causes are not well established. There has been some emphasis on mutations in developmental pathways and their impact on tumor pathology in hereditary diseases, but, in order to better understand the nature of diseases like medulloblastoma, other mechanisms also require attention.