Outcomes of adrenal-sparing surgery or total adrenalectomy in phaeochromocytoma associated with multiple endocrine neoplasia type 2: an international retrospective population-based study


CASTINETTI F., QI X., WALZ M. K. , MAIA A. L. , SANSO G., PECZKOWSKA M., ...More

LANCET ONCOLOGY, vol.15, no.6, pp.648-655, 2014 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 6
  • Publication Date: 2014
  • Doi Number: 10.1016/s1470-2045(14)70154-8
  • Title of Journal : LANCET ONCOLOGY
  • Page Numbers: pp.648-655

Abstract

Background The prevention of medullary thyroid cancer in patients with multiple endocrine neoplasia type 2 syndrome has demonstrated the ability of molecular diagnosis and prophylactic surgery to improve patient outcomes. However, the other major neoplasia associated with multiple endocrine neoplasia type 2, phaeochromocytoma, is not as well characterised in terms of occurrence and treatment outcomes. In this study, we aimed to systematically characterise the outcomes of management of phaeochromocytoma associated with multiple endocrine neoplasia type 2.