We examined the effects of carbaryl in the digestive system of Ophisops elegans. Lizards were exposed once to different concentrations of carbaryl (2.5, 25 and 250 mu g/g). After 96 h, findings related to the esophagus in all treatment groups were not conspicuous. The most important histological defects were observed in the stomach. In the small intestine, collapse of villi was prominent at high-dose. In the large intestine, disintegration in epithelial cells and scattered secretory granules of goblet cells were observed at high dose.