Investigation of the Adherence and Proliferation Characteristics of SH-SY5Y Neuron Model Cells on Graphene Foam Surfaces

Morcimen Z. G. , Tasdemir S. , Erdem C., Gunes F., ŞENDEMİR A.

15th International Conferences and Exhibition on Nanosciences and Nanotechnologies (NN) / 11th International Symposium on Flexible Organic Electronics (ISFOE), Thessaloniki, Yunanistan, 30 Haziran - 07 Temmuz 2018, cilt.19, ss.40-46 identifier identifier

  • Cilt numarası: 19
  • Doi Numarası: 10.1016/j.matpr.2019.07.654
  • Basıldığı Şehir: Thessaloniki
  • Basıldığı Ülke: Yunanistan
  • Sayfa Sayıları: ss.40-46

Özet

Graphene is a promising material for production of biocompatible surfaces with suitable physicochemical properties for effective adhesion, proliferation and differentiation of nerve cells. In this study, 3-dimensional (3D) graphene foam was synthesized via chemical vapour deposition method, and it was aimed to observe the effects of graphene foam scaffolds on SH-SY5Y dopaminergic neuron model cells before applying to clinics Raman spectroscopy, XRD and SEM analyses were performed to characterize the graphene foam. Viability of SH-SY5Y cells cultured on graphene foam scaffolds was analysed on days 1, 4 and 7 by MTT. Furthermore, cell morphology was determined by fluorescence staining of the actin cytoskeleton. (C) 2019 Elsevier Ltd. All rights reserved.