Combining radiotherapy with immunotherapy

Creative Commons License

ANACAK Y. , Kamer S., SERT F.

MARMARA MEDICAL JOURNAL, vol.28, no.4, pp.40-44, 2015 (Journal Indexed in ESCI) identifier identifier

  • Publication Type: Article / Review
  • Volume: 28 Issue: 4
  • Publication Date: 2015
  • Doi Number: 10.5472/mmj.34632
  • Title of Journal : MARMARA MEDICAL JOURNAL
  • Page Numbers: pp.40-44


It has long been known that radiation destroys the tumors by killing cells. However, immunotherapy is developing rapidly, combination of immunotherapy with chemotherapy and radiotherapy seems to be a viable option. Preclinical studies combining immunotherapy with radiotherapy resulted in promising data, where manipulating immune response enhances the effects of radiation. There are many ways of immunotherapy-radiotherapy combination, and the field is open for clinical research. This paper reviews the current situation on this topic.