Free carnitine levels in children with steroid-sensitive nephrotic syndrome


GOUSSEİNOV A. , KANTAR M. , MİR S., KESKİNOĞLU A. , ÇOKER I.

PEDIATRICS INTERNATIONAL, vol.44, no.1, pp.74-77, 2002 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 44 Issue: 1
  • Publication Date: 2002
  • Doi Number: 10.1046/j.1442-200x.2002.01505.x
  • Title of Journal : PEDIATRICS INTERNATIONAL
  • Page Numbers: pp.74-77
  • Keywords: children, free carnitine, steroid sensitive nephrotic syndrome, RENAL-INSUFFICIENCY, ABNORMALITIES, METABOLISM

Abstract

Background: Carnitine transports long-chain fatty acids accross the inner mitochondrial membrane. Carnitine metabolism is disturbed in some renal diseases, such as chronic renal failure. Previous studies have shown that children had normal serum free carnitine (FC) and total carnitine levels in idiopathic nephrotic syndrome, IgA nephropathy, non-IgA nephropathy and focal segmental glomerulosclerosis. The aim of the present study was to determine FC concentrations in plasma and urine during acute and remission periods of steroid-sensitive nephrotic syndrome (SSNS) and its association with hyperlipidemia.