Validation of Peptest (TM) in Patients with Gastro-Esophageal Reflux Disease and Laryngopharyngeal Reflux Undergoing Impedance Testing

BOR S. , Capanoglu D., VARDAR R. , Woodcock A. D. , Fisher J., Dettmar P. W.

JOURNAL OF GASTROINTESTINAL AND LIVER DISEASES, vol.28, no.4, pp.383-387, 2019 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 28 Issue: 4
  • Publication Date: 2019
  • Doi Number: 10.15403/jgld-335
  • Title of Journal : JOURNAL OF GASTROINTESTINAL AND LIVER DISEASES
  • Page Numbers: pp.383-387
  • Keywords: gastro-esophageal reflux disease, laryngopharyngeal reflux, multichannel intraluminal impedance, pepsin, Peptest (TM), NORMAL VALUES, PEPSIN, PH, RELIABILITY, VALIDITY, DIAGNOSIS, SYMPTOMS, SALIVA

Abstract

Background & Aims: Pepsin in the gastric refluxate is a marker for a prior reflux event and rapid detection might be achieved using the Peptest (TM), an in vitro diagnostic medical device. The aim of this study was to validate the use of Peptest (TM) to reliably diagnose reflux in patients with gastro-esophageal reflux disease (GERD) and laryngopharyngeal reflux (LPR) disease diagnosed with multichannel intraluminal impedance/pHmetry (MII-pH).