This study observed the effects of the alloy type, resin type, and simulated occlusal loading on enamel-resin-metal tensile bond strength. Three different dental alloy samples were sandblasted with 50 mu m of desiccant alumina and then bonded to the buccal and lingual halves of extracted human molars with four different dental resins. Specimens were divided into two groups, which included different halves of tooth samples. For one group tensile strength was tested after 19.8 N per 60,000 loading cycles. For the other group tensile testing was performed without cyclic loading. The results revealed that enamel-resin-metal bond strength was not affected by alloy type. However, a close relationship between the resin type and the bond strength was found. It was demonstrated that Panavia Ex and Concise resins produced greater bond strengths than did ABC and MBA cements. Also, a significant decrease in tensile bond strength values occurred after cyclic loading.