THE EFFECT OF SURGICAL TREATMENT ON SURVIVAL IN GERIATRIC PATIENTS WITH STAGE I SMALL-CELL LUNG CANCER


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İlkhan Daşdemir G., Çelikhisar H., Kılavuz A.

Turkish Journal Of Geriatrics-Türk Geriatri Dergisi, vol.23, no.4, pp.455-462, 2020 (Journal Indexed in SCI Expanded)

  • Publication Type: Article / Article
  • Volume: 23 Issue: 4
  • Publication Date: 2020
  • Doi Number: 10.31086/tjgeri.2020.183
  • Title of Journal : Turkish Journal Of Geriatrics-Türk Geriatri Dergisi
  • Page Numbers: pp.455-462

Abstract

Introduction: The aim of our study is to investigate the effects of early stage surgical treatment on the survival of the geriatric patient group in small cell lung cancer.

Materials and Method: Patients over 65 years of age with a diagnosis of stage I small cell lung cancer were included. The patients included in the study were divided into three groups. 1. The surgical group 2. Non-surgical group 3. Untreated group. Overall survival and lung cancer-specific survival were evaluated among these 3 groups.

Results: A total of 1248 patients were included in the study. 28.9% of the patients did not receive any treatments, 47.2% of the patients received non-surgical treatment and 23.9% of the patients received surgical treatment. The 5-year overall survival rates of the untreated group, non-surgical group and surgical group were 7%, 10% and 32%, respectively (p <0.0001). According to the results of multivariable

analysis, surgical treatment was an important factor in increasing overall survival when compared to the non-surgical treatment.

Conclusion: In patients aged 65-84 with stage I small-cell lung cancer, surgical treatment increased overall survival at a statistically significant level.