JOURNAL OF PERIODONTOLOGY, vol.78, no.10, pp.1968-1977, 2007 (Journal Indexed in SCI)
Article / Article
Title of Journal :
JOURNAL OF PERIODONTOLOGY
pathogenesis, periodontitis, polymorphism, TLR2, TLR4, TOLL-LIKE RECEPTORS, EARLY-ONSET PERIODONTITIS, INNATE IMMUNE-RESPONSE, SINGLE-NUCLEOTIDE POLYMORPHISMS, TUMOR-NECROSIS-FACTOR, ASSOCIATION, DISEASE, MUTATIONS, TLR4, RISK
Background: Toll-like receptors (TLRs) recognize exogenous ligands such as lipopolysaccharide and bacterial lipoprotein during the immune responses to pathogens. The aim of the present study was to investigate whether TLR2 and TLR4 gene polymorphisms are related to susceptibility to generalized aggressive periodontitis (GAgP).