Increased myocardial collagen turnover in patients with progressive cardiac conduction disease

Bozkaya Y. T. , AYDIN H. H. , Celik H. , Kayikcioglu M. , PAYZIN S. , Kultursay H., ...Daha Fazla

PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, cilt.31, ss.1284-1290, 2008 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 31 Konu: 10
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1111/j.1540-8159.2008.01179.x
  • Dergi Adı: PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
  • Sayfa Sayıları: ss.1284-1290

Özet

Background: Histopathologically, progressive cardiac conduction disease (PCCD) is characterized by progressive fibrosis and sclerodegenerative changes in the proximal and distal conduction system of the heart. Therefore, we sought to determine the serum levels of myocardial collagen turnover markers, extracellular matrix components, transforming growth factor beta(1) (TGF beta(1)), and bone morphogenic protein-7 (BMP-7) in this population.