Gingival crevicular fluid monocyte chemoattractant protein-1 and RANTES levels in patients with generalized aggressive periodontitis


EMINGIL G. , Atilla G. , HUSEYINOV A.

JOURNAL OF CLINICAL PERIODONTOLOGY, vol.31, no.10, pp.829-834, 2004 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 10
  • Publication Date: 2004
  • Doi Number: 10.1111/j.1600-051x.2004.00584.x
  • Title of Journal : JOURNAL OF CLINICAL PERIODONTOLOGY
  • Page Numbers: pp.829-834

Abstract

Background: Local and systemic inflammatory and immune mechanisms may be implicated in the pathogenesis of the aggressive forms of periodontal disease. Chemokines, monocyte chemoattractant protein-1 (MCP-1) and regulated on activation, normal T cells expressed and secreted RANTES (regulated on activation, normal T cells expressed and secreted), are involved in the activation and recruitment of inflammatory and immune cells to the infected sites and thereby mediating a variety of pathophysiological conditions. The aim of the present study was to examine the gingival crevicular fluid (GCF) levels of MCP-1 and RANTES in patients with generalized agressive periodontitis (G-AgP).