Relationship between glucose exposure via peritoneal dialysis solutions and coronary artery calcification in non-diabetic peritoneal dialysis patients

OK E. S. , AŞCI G. , KIRCELLI F., DUMAN S. , DHEIR H., DEMIRCI M. S. , ...More

INTERNATIONAL UROLOGY AND NEPHROLOGY, vol.44, no.6, pp.1847-1853, 2012 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 44 Issue: 6
  • Publication Date: 2012
  • Doi Number: 10.1007/s11255-012-0138-8
  • Title of Journal : INTERNATIONAL UROLOGY AND NEPHROLOGY
  • Page Numbers: pp.1847-1853
  • Keywords: Peritoneal dialysis, Glucose exposure, Coronary artery calcification, Insulin resistance, STAGE RENAL-DISEASE, CHRONIC KIDNEY-DISEASE, SMOOTH-MUSCLE-CELLS, INSULIN-RESISTANCE, HEMODIALYSIS-PATIENTS, VASCULAR CALCIFICATION, AORTIC CALCIFICATION, METABOLIC SYNDROME, CARDIOVASCULAR MORTALITY, CARDIAC CALCIFICATION

Abstract

Introduction Vascular calcification is frequent in dialysis patients and is associated with increased mortality. Impaired glucose metabolism is proposed as a contributing factor for vascular calcification. We investigated whether glucose exposure via dialysate may have a role in vascular calcification in nondiabetic peritoneal dialysis patients.