Effects of selective cyclooxygenase-2 inhibition on gingival tissue levels of prostaglandin E-2 and prostaglandin F2 alpha and clinical parameters of chronic periodontitis


VARDAR S., BAYLAS H., HUSEYİNOV A.

JOURNAL OF PERIODONTOLOGY, vol.74, no.1, pp.57-63, 2003 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 74 Issue: 1
  • Publication Date: 2003
  • Doi Number: 10.1902/jop.2003.74.1.57
  • Title of Journal : JOURNAL OF PERIODONTOLOGY
  • Page Numbers: pp.57-63

Abstract

Background: The purpose of the present study was to evaluate the effect of a relatively selective cyclooxygenase (COX)-2 inhibitor (nimesulide) and non-selective COX-1/COX-2 inhibitor (naproxen) used as an adjunct to non-surgical (scaling and root planing [SRP]) periodontal therapy in chronic periodontitis patients on the gingival tissue (GT) levels of prostaglandin (PG)E-2 and PGF(2alpha).