Effects of selective cyclooxygenase-2 inhibition on gingival tissue levels of prostaglandin E-2 and prostaglandin F2 alpha and clinical parameters of chronic periodontitis


VARDAR S., BAYLAS H., HUSEYİNOV A.

JOURNAL OF PERIODONTOLOGY, cilt.74, ss.57-63, 2003 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 74 Konu: 1
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1902/jop.2003.74.1.57
  • Dergi Adı: JOURNAL OF PERIODONTOLOGY
  • Sayfa Sayıları: ss.57-63

Özet

Background: The purpose of the present study was to evaluate the effect of a relatively selective cyclooxygenase (COX)-2 inhibitor (nimesulide) and non-selective COX-1/COX-2 inhibitor (naproxen) used as an adjunct to non-surgical (scaling and root planing [SRP]) periodontal therapy in chronic periodontitis patients on the gingival tissue (GT) levels of prostaglandin (PG)E-2 and PGF(2alpha).