This research is a comparative study of the physical properties of mechanical compact and conventional spun yarns and fabrics knitted from these yarns. To experiment the relational behavior, mechanical compact and conventional spun cotton yarns were produced in three different yarn linear densities having three twist levels. In order to examine the effect of spinning systems on fabric properties single jersey fabrics were knitted from these yarns. Results showed that, compact spun yarns have less hairiness, higher strength and higher elongation ratio than conventional spun yarns. Also, fabrics produced with compact yarns were found to have less pilling tendency.