N-acetylcysteine in patients with COPD exacerbations associated with increased sputum

AYTEMUR Z. A. , Baysak A., OZDEMIR O., KÖSE T. , SAYINER A.

WIENER KLINISCHE WOCHENSCHRIFT, cilt.127, ss.256-261, 2015 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 127
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1007/s00508-014-0692-4
  • Dergi Adı: WIENER KLINISCHE WOCHENSCHRIFT
  • Sayfa Sayısı: ss.256-261

Özet

Background N-acetylcysteine (NAC) has been shown not to alter the clinical outcome in chronic obstructive pulmonary disease (COPD) exacerbations. However, NAC may improve symptoms through its mucolytic effect in the subgroup of patients with increased sputum production. The aims of this study were to determine whether NAC improves symptoms and pulmonary function in patients with COPD exacerbation and increased sputum production.