N-acetylcysteine in patients with COPD exacerbations associated with increased sputum

AYTEMUR Z. A. , Baysak A., OZDEMIR O., KÖSE T. , SAYINER A.

WIENER KLINISCHE WOCHENSCHRIFT, vol.127, pp.256-261, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 127
  • Publication Date: 2015
  • Doi Number: 10.1007/s00508-014-0692-4
  • Title of Journal : WIENER KLINISCHE WOCHENSCHRIFT
  • Page Numbers: pp.256-261

Abstract

Background N-acetylcysteine (NAC) has been shown not to alter the clinical outcome in chronic obstructive pulmonary disease (COPD) exacerbations. However, NAC may improve symptoms through its mucolytic effect in the subgroup of patients with increased sputum production. The aims of this study were to determine whether NAC improves symptoms and pulmonary function in patients with COPD exacerbation and increased sputum production.