A Novel Glycoside from Acanthus hirsutus (Acanthaceae)


CAPANLAR S., BOKE N. , YAŞA İ. , Kirmizigul S.

NATURAL PRODUCT COMMUNICATIONS, cilt.5, ss.563-566, 2010 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 5 Konu: 4
  • Basım Tarihi: 2010
  • Dergi Adı: NATURAL PRODUCT COMMUNICATIONS
  • Sayfa Sayısı: ss.563-566

Özet

A novel glycoside, hirsutusoide (1), characterized as 2-(o-hydroxyphenyl)-2-hydroxyethenyl-O-beta-glucopyranoside, was isolated from the endemic Acanthus hirsutus Boiss. In addition to compound 1, three known glycosides, luteolin-7-O-beta-D-glucuronide (2), beta-sitosterol-3-O-beta-D-glucopyranoside (3) and (2R)-2-O-beta-D-glucopyranosyl-2H-1,4-benzoxazin-3(4H)-one (4), were also isolated. Compound 2 was the first report from this genus. Antimicrobial and antioxidant activity of the extracts and the novel compound were investigated by determining MIC (mu g/mL) and IC50 (mu g/mL) values, respectively.