A randomised comparison of the effects of nebivolol and atenolol with and without chlorthalidone on the sexual function of hypertensive men


Boydak B. , Nalbantgil S., Fici F., Nalbantgil I., Zoghi M. , Ozerkan F. , ...More

CLINICAL DRUG INVESTIGATION, vol.25, no.6, pp.409-416, 2005 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 25 Issue: 6
  • Publication Date: 2005
  • Doi Number: 10.2165/00044011-200525060-00006
  • Title of Journal : CLINICAL DRUG INVESTIGATION
  • Page Numbers: pp.409-416

Abstract

Background and objective: Erectile dysfunction, which is common in men with hypertension, has been reported as a common adverse effect of many anti hypertensive drug classes, including P-blockers and diuretics. Atenolol and nebivolol are both beta(1)-selective blockers, but nebivolol is a new-generation compound with nitric oxide-mediated vasodilating activity. The aim of the study was to compare the effects of nebivolol and atenolol +/- chlorthalidone on the sexual function of hypertensive men.