Variable sonographic spectrum of parathyroid adenoma with a novel ultrasound finding: dual concentric echo sign


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Acar T., ÖZBEK S. S. , ERTAN Y. , KAVUKÇU G. , TUNCYUREK M., İÇÖZ R. G. , ...More

MEDICAL ULTRASONOGRAPHY, vol.17, no.2, pp.139-146, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 2
  • Publication Date: 2015
  • Doi Number: 10.11152/mu.2013.2066.172.tka
  • Title of Journal : MEDICAL ULTRASONOGRAPHY
  • Page Numbers: pp.139-146

Abstract

Aims: To review the detailed gray-scale and Doppler ultrasonography features of histologically proven parathyroid adenomas (PAs) evaluated with high-end ultrasonography devices and to present a novel ultrasonography finding called the dual concentric echo sign in PA with histopathologic correlation which was encountered during detailed analysis. Material and methods: Fifty-six PAs with histopathological result were enrolled. The longest dimension, shape, distance to skin surface, internal echo and Doppler US features obtained with high-end US devices were evaluated. Results: PAs had variable range of shape including oval, irregular, fusiform, lobulated, crescent-shaped, and nodular configuration. In nine patients the lesions were shown to have cystic components and calcifications were seen in four cases. Dual concentric echo sign was detected in 18% PAs. Histological reevaluation of this subgroup demonstrated significantly increased edema (p<0.01), and ectatic vessels (p=0.02) in the central part of the lesion compared to the rest of the PAs. Conclusions: The results of the study led to the conclusion that PAs have variable gray-scale and Doppler findings. Typical sonographic features like ovoid shape, homogeneously hypoechoic pattern may not be present in all PAs. Dual concentric echo sign which is a novel sonographic pattern may be suggestive of a PA.