Infliximab: a new therapeutic agent in acute pancreatitis?


Oruc N. , Ozutemiz A. Ö. , Yukselen V., Nart D., Celik H. , Yuce G., ...More

Pancreas, vol.28, no.1, 2004 (Journal Indexed in SCI Expanded) identifier identifier identifier

Abstract

Purpose: Tumor necrosis factor alpha (TNF-alpha) has a central role in the pathogenesis of acute pancreatitis and related systemic complications. The aim of this study is to investigate the therapeutic effectiveness of monoclonal TNF antibody (infliximab) in acute edematous and severe necrotizing pancreatitis models in rats.