Screening of Natural Product and Natural Product like Molecules against SARS-CoV-2 Main Protease Using Molecular Modeling Methods


AKGÜN İ. H.

JOURNAL OF PHARMACEUTICAL RESEARCH INTERNATIONAL, vol.32, no.48, pp.36-51, 2020 (Journal Indexed in ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 32 Issue: 48
  • Publication Date: 2020
  • Doi Number: 10.9734/jpri/2020/v32i4831123
  • Title of Journal : JOURNAL OF PHARMACEUTICAL RESEARCH INTERNATIONAL
  • Page Numbers: pp.36-51
  • Keywords: SARS-CoV-2, natural products, virtual screening, docking, molecular dynamics, bioactive molecule design, DRUG DISCOVERY, LIBRARIES

Abstract

Objective: To determine possible M-Pro enzyme inhibitors by using structure-based virtual screening methods, in the ZINC Biogenic Data Set containing natural products and natural product-like molecules.