Immune status and autoantibody formation in children with chronic hepatitis B infection

UNAL F., GENEL F., OZGENC F., Aksu G. , AYDOGDU S., Kutukculer N. , ...More

PANMINERVA MEDICA, vol.44, no.4, pp.353-357, 2002 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 44 Issue: 4
  • Publication Date: 2002
  • Title of Journal : PANMINERVA MEDICA
  • Page Numbers: pp.353-357


Background. The hepatitis B virus (HBV) causes a wide spectrum of disease which ranges from acute hepatitis to liver cirrhosis. Patients who fail to mount a vigorous immune response in acute HBV develop chronic infection. Therefore, the aim of the study was to determine the cellular and humoral immune parameters of the patients with chronic HBV and to evaluate the prevalence of autoantibodies before the beginning of immunomodulator and antiviral therapy.