DO ANALOGS OF GONADOTROPIN-RELEASING-HORMONE INFLUENCE FOLLICULAR-FLUID STEROID-LEVELS, OOCYTE MATURITY AND FERTILIZATION RATES


TAVMERGEN E. , TAVMERGEN E. , CAPANOGLU R.

HUMAN REPRODUCTION, vol.7, no.4, pp.479-482, 1992 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 7 Issue: 4
  • Publication Date: 1992
  • Doi Number: 10.1093/oxfordjournals.humrep.a137674
  • Title of Journal : HUMAN REPRODUCTION
  • Page Numbers: pp.479-482

Abstract

One-hundred-and-twelve samples of follicular fluid from 32 patients undergoing in-vitro fertilization and embryo transfer were analysed in this study. The follicular fluids were analysed for any relationships between oestradiol, progesterone and 17-alpha-hydroxyprogesterone levels, the progesterone/oestradiol and 17-alpha-hydroxyprogesterone/oestradiol ratios and oocyte maturity and fertilization rates. In Group A, consisting of women who used analogues of gonadotrophin-releasing hormone during ovarian stimulation with human menopausal gonadotrophin, the progesterone/oestradiol ratio rose in parallel with the fertilization rate (P < 0.05). Group B comprised patients treated with human menopausal gonadotrophin alone. No significant relationship was found between the other parameters, oocyte maturation and fertilization rates in either group.