Tryptamine derived amides with thiazole ring system from Thermoactinomyces strain TA66-2

Akmemıs Korkmaz C., Hames E. E. , Uzel A. , Bedir E.

MAGNETIC RESONANCE IN CHEMISTRY, cilt.46, ss.80-83, 2008 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 46
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1002/mrc.2101
  • Dergi Adı: MAGNETIC RESONANCE IN CHEMISTRY
  • Sayfa Sayısı: ss.80-83

Özet

A moderately thermophilic actinomycete strain, which was identified as Thermoactinomyces strain TA66-2, was isolated from hot-spring water. Fermentation, followed by solvent partition and chromatographic separations, resulted in the isolation of two new and two known molecules. The structures of the new compounds were elucidated as 2-(1-Propionylaminoethyl)thiazole-4-carboxylic acid [2-(1H-indol-3-yl)ethyl]amide and 2-(1-Acetylaminoethyl)thiazole-4-carboxylic acid [2-(1H-indol-3-yl)-ethyl]amide by using spectral methods (1D-, 2D-NMR and LC-ESI-MS). Copyright (C) 2007 John Wiley & Sons, Ltd.